and phase-II (conjugating) enzymes have been extensively studied. This review introduces the concept of pharmacogenetics in the context of drug-metabolizing enzymes and highlights the ...

The NMR and Drug Metabolism Core has developed rapid and efficient approaches ... The half-life of a drug (t 1⁄2), absorption and tissue distribution are important properties for first-pass success of ...

Feb. 06, 2025 (GLOBE NEWSWIRE) -- Denali Therapeutics Inc. (NASDAQ: DNLI), today announced the primary analysis of the Phase 1/2 study in 47 participants with ... Genetics, Genomics and Metabolism at ...

AnaptysBio may have ended last year on a low, but 2025 is looking up with the news that its PD-1 agonist rosnilimab has ...