The new Dogma meets Thomas Kuhn’s definition of a paradigm shift. The DNA/RNA Dogma is sufficiently unprecedented to attract ...

Proteomic analysis provides scientists with a deeper understanding of the molecular events that influence health and disease.

The term "phenotype" refers to the observable physical properties of an organism; these include the organism's appearance, development, and behavior. An organism's phenotype is determined by its ...

In general, when we know that the genotype is present but the phenotype is not observable, the trait shows incomplete penetrance. Basically, anything that shows less than 100% penetrance is an ...

This variability may be part of a bet-hedging strategy, where populations express a range of phenotypes to ensure survival in unpredictable environments. In addition phenotypic variability between ...

If you get a mutation in coding DNA, then the sequence of DNA could be changed. Changing the sequence of DNA can change the amino acids that make up the protein. This could have huge consequences.

The FDA has accepted for review the BLA for mepolizumab as an add-on maintenance treatment for eosinophilic COPD.

British drug maker GSK plc (GSK, GSK.L) announced Monday that the U.S. Food and Drug Administration has accepted for review, data ...

A new pregnancy health cohort study involving over 20,000 families has identified common complications, high-risk groups, and geographical trends through biological samples collected across China ...

Multiplexed assays of variant effect are an increasingly important tool in genetic research and including more context specificity in their design would aid interpretation and discovery.