Previous efforts to circumvent the problem of the size limitation imposed by the AAV vector have focused mainly on altering the candidate genes into ‘mini-expression cassettes’ suitable for ...
Recombinant AAV are capable of transducing a broad ... a new method based on microarray technology. In a transfection microarray, plasmid DNA dissolved in a gelatin solution is printed on a ...
Production system: Today's launch introduces Asimov’s transient transfection-based AAV manufacturing system ... an optimized two-plasmid system compatible across capsid serotypes; and model ...