Post-translational modifications are modifications ... here the authors show that the methyltransferase METTL1 drives B cell activation via the tRNA m 7 G modification-dependent translation ...
Figure 1: Mechanisms of rapid non-genomic receptor-dependent actions of estrogen in four cell types. E2 induces MAPK phosphorylation and activation within 5 minutes in osteoblasts (ref.
is the first and most advanced asset from BeiGene’s chimeric degradation activation compound (CDAC) platform. Oral presentation of the BGB-11417-101 Phase 1 study demonstrated B-cell lymphoma 2 ...