Discover how next-generation kinase inhibitors are transforming clinical therapy byovercoming resistance and enhancing ...

(IGF1, insulin-like growth factor 1; MAPKAP-K1, mitogen-activated protein kinase (MAPK)-activated protein kinase 1; PDK1, 3-phosphoinositide-dependent protein kinase 1; PKB/AKT, protein kinase B ...

A new review published in Genes & Diseases explores the multifaceted role of FAM20C, a Golgi protein kinase, in disease ...

In cancers, all translocations involving ALK produce fusion proteins with constitutive tyrosine kinase activity that ... Activation of the phospholipase C-γ (PLCγ) pathway is also thought ...