AlphaGalileo15h
Phosphorylation and dephosphorylation enzyme groups regulate sleep and wakefulness in mammals
A research group of The University of Tokyo has discovered that in mammals, a protein kinase A (PKA) promotes wakefulness, ...
eLife8d
Water and chloride as allosteric inhibitors in WNK kinase osmosensing
WNKs sense osmotic pressure by binding specific water molecules to the inactive dimeric configuration of WNK1 and WNK3, integrating signals with chloride inhibition as demonstrated by mutagenesis and ...