Genzyme Corp. (Sanofi Genzyme) has identified receptor-interacting serine/threonine-protein kinase 1 (RIPK1; RIP-1) inhibitors reported to be useful for the treatment of Alzheimer’s disease, multiple ...

Novel macrocyclic heteroaryl derivatives acting as non-receptor tyrosine-protein kinase TYK2 and/or JAK1 and/or JAK2 inhibitors have been reported in a Hangzhou Highlightll Pharmaceutical Co. Ltd.

In this randomized controlled trial, among adults diagnosed with chronic myeloid leukemia (CML), asciminib demonstrated a ...

SELLAS Life Sciences Group has announced positive data from preclinical studies identifying the ASXL1 mutation as a ...

A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights ...

WNKs sense osmotic pressure by binding specific water molecules to the inactive dimeric configuration of WNK1 and WNK3, integrating signals with chloride inhibition as demonstrated by mutagenesis and ...

A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights into how it functions.

As Ahmet F. Coskun and his team of researchers continue their mission to create a 3D atlas of the human body, mapping cells ...

With the support of the RiDYMO® platform, we are able to comprehensively explore various potential targets in drug ...

Hutchmed announces continued inclusion of Orpathys in the National Reimbursement Drug List in China at current terms: Hong Kong, Shanghai Saturday, November 30, 2024, 16:00 Hrs [I ...

SignalChem Biotech provides diverse recombinant Tau proteins for research, helping advance tau-targeted therapies that may ...