To develop a small-molecule drug, researchers spend years ... called structure-based drug design. The 3-D structure of many proteins remained unavailable, and many important proteins could not ...

This article was originally published with the title “ The Three-Dimensional Structure of a Protein Molecule ” in Scientific American Magazine Vol. 205 No. 6 (December 1961), p. 96 doi:10.1038 ...

The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

Artificially designed proteins are usually based on building blocks that obey strict rules of symmetry. As such, their ...

Scientists still needed to figure out this molecule's structure to be sure, and to understand how it worked. In 1948, Linus Pauling discovered that many proteins take the shape of an alpha helix ...

These DZBB assemblies serve as a versatile foundation for molecular ... for synthesizing proteins in cells. This evolutionary ...

“Not just the spatial structure of the protein but how it changes over time, and that seemed like a perfect match for sound as sound doesn’t even exist without time.” Usually, scientists visualize ...

revealed the specific shape and structure of one of the body's most important yet complicated proteins: ApoB100. Acting as a kind of molecular exoskeleton, this protein wraps around LDL particles ...

A research team at POSTECH (Pohang University of Science and Technology) has successfully developed a super-photostable ...