In fact, each gene in cellular DNA contains the code for a unique protein structure. Not only are these proteins assembled with different amino acid sequences, but they also are held together by ...

But not all target proteins were receptive to this method, called structure-based drug design. The 3-D structure of many proteins remained unavailable, and many important proteins could not be ...

These bonds are dynamic, rapidly forming and breaking over time as the protein folds. Because it only takes nanoseconds to microseconds for a protein to morph along its path to its final structure, ...

View Full Profile. Learn about our Editorial Policies. Jumper and Hassabis led the AlphaFold team that revolutionized the field of structural biology by accelerating the process of protein structure ...