近期中国科学院武汉病毒研究所彭珂团队在国际学术期刊PLoS Pathogens发表了题为“RVFV virulence factor NSs triggers the mitochondrial MCL-1-BAK axis to activate ...

从狩猎伙伴到家庭成员，狗的温顺、忠诚和善解人意，使它们赢得无数“铲屎官”的心。然而，近年来，随着一系列恶犬伤人事件的频繁发生，这一和谐景象背后隐藏的健康风险也逐渐浮出水面，引起了社会各界的广泛关注和深入讨论。对狂犬病毒的研究与防控，也成为了公共卫生领 ...

8月19日，中国科学院成都生物研究所生物资源利用中心王飞研究团队联合四川大学化学学院冯小明院士和董顺喜教授团队在药物化学国际顶级期刊Journal of Medicinal Chemistry上发表题为“Discovery of a Covalent Inhibitor of Pro-Caspase-1 Zymogen Blocking NLRP3 Inflammasome Activation ...

中国科学院武汉病毒研究所彭珂团队在国际学术期刊PLoS Pathogens发表了题为“RVFV virulence factor NSs triggers the mitochondrial MCL-1-BAK axis to activate pathogenic NLRP3 pyroptosis”的研究论文 ...

Halia Therapeutics, Inc. (Halia), a clinical-stage biopharmaceutical company pioneering innovative treatments for inflammatory and neurodegenerative diseases, today announced that it will showcase its ...

Psoriasis is a multifactorial immune-mediated inflammatory disease. Its pathogenesis involves abnormal accumulation of neutrophils and T-cell related abnormalities. Pyroptosis is a type of regulated ...

This valuable study on strategies used by Pseudomonas to subvert hots immunity identifies a new immune evasion strategy. The study presents solid evidence on the cleavage of VgrG2B by Caspase 11 and ...

Activation of NLRP3 triggers the release of the pro-inflammatory cytokines IL-1β and IL-18 and induces a lytic cell death process called pyroptosis. These processes lead to systemic chronic ...

Retraction Note: M2 macrophage-derived extracellular vesicles promote gastric cancer progression via a microRNA-130b-3p/MLL3/GRHL2 signaling cascade. Retraction Note ...

Pyroptosis results in systemic release of inflammatory cytokines, IL-1β and IL-18, and ASC specks, w Neurological diseases, which affect up to 16 million people over 18 years old in the US ...