What actually happens in the brain in cases of depression? Relatively unknown brain cells—"astrocytes"—are believed to play ...

New research shows astrocytes can remove Alzheimer’s-related amyloid-beta via autophagy, offering a promising new direction ...

A new cluster of reactive astrocytes emerged, with varied gene expression linked to neurogenic and reactive phenotypes.

(A) Increased expression of autophagy factors (LC3B, observed as blue dots) in astrocytes (GFAP) in the brain tissues of AD patients. (B) Increases in reactive astrocytes and autophagy gene ...

Brains of five-week-old mice whose Htt was deleted show signs of cellular stress -- reactive astrocytes (green) and microglia (white and red) and faulty connections -- in brain circuits that have ...

The group demonstrated a mechanism where the astrocytes in the brain uptake elevated levels of acetates, which turns them into hazardous reactive astrocytes. The researchers then developed a new ...

Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acetate uptake in primary cultured astrocytes.

A key aspect of PD pathophysiology is neuroinflammation in the nigrostriatal pathway, including the presence of reactive astrocytes. This neuroinflammation has long been considered a downstream ...

Early observations suggest that the vehicle-treated Alzheimer's mice exhibit a larger population of reactive astrocytes, while the HT-ALZ treated groups show fewer reactive astrocytes, pointing to a ...