1a,b). Mutation of two amino acid residues (190 and 225) in the hemagglutinin protein that switched the virus' receptor binding preference from human α-2,6 sialic acid to avian α-2,3 sialic acid ...
Sialic acid (blue links) at the end of sugar chains attached to antibodies (red) induce the antibodies to bind to receptors (light blue) that promote an anti-inflammatory response in alveolar ...
3 receptor plentiful in birds to the alpha 2,6 sialic acids plentiful in the human nose, throat and lungs. One place in the human body where alpha 2,3 receptors are plentiful is the eye ...
WEI Wei from IPE. Extending beyond SARS-CoV-2, the researchers replaced the ACE2 protein receptor with the sialic acid (SA) saccharide receptor and again found potent clearance of influenza A by ...