High levels correlated with mild symptoms; sicker patients’ antibodies sported fewer sialic acid links. Wang and her colleagues explored further, using bioengineered mice whose cells expressed human ...
Sialic acid (blue links) at the end of sugar chains attached to antibodies (red) induce the antibodies to bind to receptors ...
Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have recently developed a ...
Wang and her colleagues explored further, using bioengineered mice whose cells expressed human receptors for antibodies. "We gave the mice human antibodies differing only in their sialic acid ...
The initial steps of viral infection involve the specific attachment of the viral particle to receptor(s ... including sialic acid, various integrins, heat shock protein 70 and gangliosides.
1a,b). Mutation of two amino acid residues (190 and 225) in the hemagglutinin protein that switched the virus' receptor binding preference from human α-2,6 sialic acid to avian α-2,3 sialic acid ...
3 receptor plentiful in birds to the alpha 2,6 sialic acids plentiful in the human nose, throat and lungs. One place in the human body where alpha 2,3 receptors are plentiful is the eye ...