Typically, TriAx antibodies target tumor-associated antigens and engage T cell receptors to redirect T cell cytotoxicity. These heterodimeric antibodies are designed primarily for the generation ...
In doing so, the bispecifics redirect T cells of any specificity to target cells. ImmTAX molecules have inherent advantages over other modalities. The molecules recognize peptides derived from ...
The firms partnered earlier this year to leverage each other's technologies and develop multiple T-cell receptor-guided T-cell engagers.
In some instances of rhabdomyosarcoma, a rare cancer arising from muscle cells stalled in their journey toward their final non-dividing state, mutations to MyoD’s DNA-binding region redirect the ...