Necroptosis is the predominant form of neuronal death after ischemic stroke. This study identifies the deubiquitinating enzyme OTUB2 as a novel regulator of the RIPK1-RIPK3-MLKL necroptotic signaling ...
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Geneticists develop world's first bioinformatic tool to identify amyloids consisting of multiple copies of same proteinOn the other hand, some important biological processes require co-aggregation of different amyloid-forming proteins. Among known examples of the co-aggregation are human proteins RIPK1 and RIPK3.
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