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27 天
明星靶点「STAT3」肿瘤研究与靶向治疗的重要方向
STAT3是一种在多种组织中表达的信号分子,调控一系列与癌细胞生长、增殖、血管生成、转移、耐药性和免疫逃逸等有关的基因。因此,靶向 STAT3 ...
15 天
揭秘:细胞因子、炎症与癌症的交汇点,JAK-STAT信号通路引领新药研发!
JAK-STAT信号通路,自1992年被科学家首次揭示以来,对细胞通讯、免疫调节、肿瘤发生发展等关键生物学过程的理解产生了深远影响。迄今为止,与此通路相关的科学论文已超过10万余篇,对生命科学和医学的发展做出了巨大贡献。
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