Three groups of selectins exist: E-selectin (CD62E), P-selectin (CD62P) and L-selectin (CD62L). Each group interacts with its corresponding glycoprotein (mucin) ligands on particular tissues.

Anti-P-selectin antibody Adakveo became the first new treatment for VOCs in SCD patients in decades when it was approved for marketing in the EU, a few months after the FDA gave it the nod in the ...