Hepatocellular carcinoma (HCC) is one of the deadliest malignant tumors in the world, and its incidence and mortality have increased year by year. HCC research has increasingly focused on ...

Mapping the key signaling molecules in biochemical pathways will be central to future drug discovery efforts. Signal transduction describes the process of conversion of external signals ...

These intracellular signaling pathways, also called signal transduction cascades, typically amplify the message, producing multiple intracellular signals for every one receptor that is bound.

Davis, University of Massachusetts Medical School, Howard Hughes Medical Institute. The signal transduction pathways of mitogen-activated protein (MAP) kinases have been actively studied for some time ...

The main goal of our laboratory is the identification and characterization of signal transduction pathways that cause the dysregulation of growth and inhibition of apoptosis that characterize advanced ...

The main goal of our laboratory is the identification and characterization of signal transduction pathways that cause the dysregulation of growth and inhibition of apoptosis that characterize advanced ...

Members of the program engage in research aimed at obtaining a mechanistic understanding of signal transduction and cellular regulation, which includes cellular signaling pathways and downstream ...

The findings highlight the significance of frequency-selective cellular responses in developmental biology, providing valuable insights into the intercellular signal transduction mechanisms.

My current laboratory interests are directed at determining methods of manipulating signal transduction pathways to enhance radiation sensitivity." ...

Attisano, J.L. Wrana, "MADR1, a MAD-related protein that functions in BMP2 signaling pathways," Cell ... If there is one thing that is known about the mechanisms that govern signal transduction, it's ...