Lessons learned from these two model organisms also apply to cells that divide asymmetrically in other metazoans, such as self-renewing stem cells in mammals. Asymmetric cell division is crucial ...
If cells are removed from the embryo they will differentiate into any cell type. These are called embryonic stem cells. Some stem cells remain in the bodies of adults as adult stem cells.
for example bone marrow transplants, corneal transplants, and skin grafts for burns. Stem cells have also been used as model cells to study how diseases develop or for drug testing.
We discovered that interferon gamma (IFNγ) promotes hematopoietic stem cell (HSC) division and myeloid differentiation in a mouse model of Mycobacterium avium infection (Nature 2010). Furthermore, ...
The goal of the Stem Cell program is to conduct rigorous scientific studies to enhance our knowledge of normal and altered stem cell development and to advance treatments and improve outcomes for ...
Resolving how cell of origin affects pathways that govern progression of precancerous lesions will ultimately allow us to develop methods to detect PDAC early, which is arguably the most important ...
Its development is tightly controlled by genetic and epigenetic programs. Stem cell-based embryo models, such as blastoids, serve as models of the blastocyst and are invaluable tools for studying ...
iPSC-derived, disease-specific cell models serve as an opportunity ... GoEditStem platform and the Stem Cells and Biomaterials consortium, national Biocenter Finland technology platform. BSCC is ...