for example bone marrow transplants, corneal transplants, and skin grafts for burns. Stem cells have also been used as model cells to study how diseases develop or for drug testing.
Stem cells close stem cellA cell found in foetuses, embryos and some adult tissues that can give rise to a wide range of other cells. can divide to produce new cells, which can then divide into ...
Lessons learned from these two model organisms also apply to cells that divide asymmetrically in other metazoans, such as self-renewing stem cells in mammals. Asymmetric cell division is crucial ...
We discovered that interferon gamma (IFNγ) promotes hematopoietic stem cell (HSC) division and myeloid differentiation in a mouse model of Mycobacterium avium infection (Nature 2010). Furthermore, ...
The goal of the Stem Cell program is to conduct rigorous scientific studies to enhance our knowledge of normal and altered stem cell development and to advance treatments and improve outcomes for ...
Resolving how cell of origin affects pathways that govern progression of precancerous lesions will ultimately allow us to develop methods to detect PDAC early, which is arguably the most important ...
Its development is tightly controlled by genetic and epigenetic programs. Stem cell-based embryo models, such as blastoids, serve as models of the blastocyst and are invaluable tools for studying ...
Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists used state-of-the-art ...