Excitatory synapses are located in confined chemical spaces called the dendritic spines. These are atypical femtoliter-order microdomains where the behavior of even single molecules may have ...
Nestin, a well-known stem cell marker, regulates the formation of neuromuscular junctions (shown in yellow), the contact points between muscles cells and "their" motor neurons (shown in green).
When naive T cells encounter antigen-presenting cells (APCs), membrane and cytoplasmic molecules rearrange at the T cell–APC contact area to form the immune synapse. Finetti et al. now reveal an ...
The background is an image of neurons (blue). Some of them express the new amyloid precursor protein reporter (green) and a synapse-marker, Synaptophysin-pHTomato (red). The rendering at the lower ...
An electrical impulse cannot directly cross the gap so a different mechanism has to be used. Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ...