Regulatory T cells (Tregs) have gone from obscurity to rock-star status in the past decade, prompting intense scrutiny—but what exactly are they? Four studies examine this question, delving ...
In a recent article, researchers explored how calcium carbonate nanoparticles enhance T cell activation through calcium ...
Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...
CD3-binding antibodies to widen the therapeutic window by generating TCEs with potent tumor-cell killing and ... indications by increasing T-cell activation and proliferation through costimulation ...
This study presents important findings on the role of CXXC-finger protein 1 in regulatory T cell gene regulation and function. The evidence supporting the authors' claims is solid, with mostly ...
One-third of HER2-positive (HER2+) tumors express the P95HER2 protein, which associates with an aggressive form of breast ...
The first computer algorithm capable of identifying which tumor cells are driving aggressive cancer growth has been developed ...
Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells ...