Cancer cells impair monocyte-mediated T-cell activation by disrupting inflammatory pathways in the tumor microenvironment.
Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...
In a recent article, researchers explored how calcium carbonate nanoparticles enhance T cell activation through calcium ...
Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells ...
By inferring proliferation rates from single-cell genomics, SPRINTER enhances understanding of tumor evolution and identifies ...
Despite its successes, CAR T-cell therapy faces challenges as treatment for solid tumors," said Joaquín Arribas. Tumors driven by HER2 overexpression In normal amounts, HER2 plays a crucial role in ...