B, a transcription factor, is essential for maintaining X chromosome inactivation in T cells, connecting immune activation to ...

Instead, early IL-2 production by the T cells during their initial contact with LSECs was found to be responsible for overriding the tolerogenic response. Functional inactivation of IL-2 by ...

In the anxious brain— whether through overexcitability of the stress response system, the activity of various neurochemicals, impairments in nerve circuitry, or inactivation of specific cell ...

Researchers have identified the origin of ovarian cancer that develops in the fallopian tube, which opens doors to ...

Loss of CDK12 inactivated TRP53 but showed negative correlations with the inactivation of PTEN ... proliferation and immune infiltration by T cells with elevated cytokine levels.

“Black individuals are more likely to live in areas with elevated levels of air pollution, including diesel exhaust and other ...

This valuable study addresses potential roles of the master regulator of X chromosome inactivation, the Xist long non-coding RNA, in autosomal gene regulation. Using data from mouse cells, the authors ...

F.M. Yavitt, B.E. Kirkpatrick, M.R. Blatchley, K.F. Speckl, E. Mohagheghian, R. Moldovan, N. Wang, P.J. Dempsey and K.S. Anseth, “In situ modulation of intestinal ...