T cell lineage maturation is a highly regulated process requiring intact DNA repair capacity 1,2. BRCA1 (breast cancer 1, early onset) is a tumor suppressor that probably has a DNA repair function.
Discover how the emerging field of using CAR-T cell therapy to treat lupus could offer a potential cure for the autoimmune ...
A novel test enables real-time monitoring of T cells that have been engineered to fight cancer, after re-introduction into the body of a cancer patient. This simple and innovative test provides ...
SciTech Development, a clinical-stage pharmaceutical company focused on advancements in cancer treatment, is excited to share ...
They also applied CRISPR screening to identify which regulators help control T cell fate development into Th1 vs. Th2 cells.