Study identifies 'turncoat' cells that fight—and aid—cancer
Yale researchers have made an unexpected discovery—turncoat T cells that help a tumor evade other cancer-fighting immune T ...
Medical Xpress on MSN15d
Researchers identify gene signature for high-risk form of T-cell acute lymphoblastic leukemia
The researchers identified a subpopulation of bone-marrow progenitor-like (BMP-like) T-ALL associated with treatment failure ...
Nature8d
CD8-positive T cells articles from across Nature Portfolio
CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...
Researchers reveal how aging impairs antitumor activity of CD8⁺ T cells
A research team from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences has revealed that aging specifically impairs the generation of CD8+ tissue resident memory ...
Study identifies key cell subpopulation and associated gene signature in neuroblastoma
In conclusion, this study provides a detailed molecular roadmap of NB's metastatic journey, identifying a key cell ...
News Medical on MSN15d
Children’s Hospital of Philadelphia researchers identify gene signature for high-risk form of T-cell acute lymphoblastic leukemia
The researchers identified a subpopulation of bone-marrow progenitor-like (BMP-like) T-ALL associated with treatment failure and overall poor survival. Progenitor cells are descendants of stem cells ...
Nature12d
Cytotoxic T cells articles from across Nature Portfolio
Tumor-antigen-specific CD8 + T cells are generally thought to help fight against cancer, but here the authors identify a subpopulation of CD8 + T cells that are associated with a poor clinical ...