据丁香园Insight数据库,截至目前(数据截至2024年11月19日)全球范围内蛋白降解研发管线项目总数已过千,其中超过95款处于临床开发阶段。
Tampa police are warning the community about a scam that targets people looking to use mobile payment methods in city parking ...
A New Hampshire jury on Tuesday found a former leader at a youth detention center guilty of holding down a teen while he was ...
图1靶向蛋白降解胞吞-降解作用新机制 靶向蛋白降解(TPD)是当今生物医药领域的热门研究方向,通过TPD分子将疾病相关蛋白牵引至细胞内的“回收站”进行降解清除,为传统药物难以成药的蛋白质提供了巨大的治疗潜力。但现有的TPD分子为适应不同的疾病靶点 ...
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TPD investigating 19th homicide
Topeka Police Department is investigating the 19th homicide of 2024.Sunday night, officers responded to a reported shooting ...
TALLAHASSEE, Fla. (WCTV) - The Tallahassee Police Department held a promotion ceremony Tuesday morning at city hall. Chief ...
Prazer’s proprietary TPD platform, selective protein degradation enabling moiety (SPiDEM), allows the rational design and rapid optimization of orally available and BBB-penetrating small molecules.
The Topeka Police Department (TPD) is investigating a shooting that happened Friday evening in North Topeka. Just after 5:30 ...
TOLEDO, Ohio (WTVG) - A man faces multiple felony charges for allegedly assaulting a woman before forcing her into a vehicle ...
复旦大学生命科学学院鲁伯埙和丁澦受《 Cell 》杂志主编 Luis Gomes 邀请,撰写了题为 Targeted Degradation Technologies 的 SnapShot ,系统介绍了靶向降解技术的发展现状、主要类别、作用机制及其在药物发现中的应用潜力,该文于 2024 年 11 月 14 日在《 Cell 》上正式发表 ...