How many naive T cells that are specific for any one peptide–MHC complex exist in an individual? How does that number influence the immune response? Answers to these questions have remained ...

Use of murine b2-microglobulin may reduce the stability of the reagent. Typically staining of murine CD8+ T-cells with tetramer is NOT affected by the use of human b2-microglobulin. One of the factors ...