Overall, the new immunosuppressive agents tacrolimus, sirolimus and MMF have significant clinical roles in solid organ transplantation, but they have narrow therapeutic ranges and numerous toxicities.

Patients in the anti-Xa HA group also had more test values within the therapeutic range (66% vs 42%, p < 0.0001). A significant difference was seen between the 2 groups in the number of aPTT or ...

Overall, the findings underscore mitochondria's essential role beyond energy production and suggest that mitochondria may be a promising therapeutic target for treating a range of inflammatory ...