Background Mutations in the bile acid (BA) transporter genes can result in intrahepatic cholestasis of pregnancy (ICP), cholelithiasis and progressive familial intrahepatic cholestasis. Severe ICP is ...

PubMed Dig Dis. 2017;35:217-223. The emerging role of soluble adenylyl cyclase in primary biliary cholangitis. Chang JC, Beuers U, Oude Elferink RP. PubMed Lancet. 2017:389:1114-1123. Effect of ileal ...

The Breakthrough Therapy designation is supported by positive interim data from the phase 2b VANTAGE study (ClinicalTrials.gov Identifier: NCT05050136) that evaluated the efficacy and safety of ...

Mirum Pharmaceuticals, Inc. is a biopharmaceutical company dedicated to transforming the treatment of rare diseases affecting ...

Biliary atresia is when a newborn has blocked tubes in the liver. These tubes, called bile ducts, carry bile from the liver to the small intestine. If they’re blocked, bile builds up in the liver and ...

The posters will be made available on the Rectify website following the presentations.