T cells are central to the body's defense ... anti-tumor immunity is an emerging area in cancer therapy, systemically inhibiting Tregs can cause severe autoimmune reactions. This challenge has ...
Nonetheless, low Foxp3 differentiated Tregs into Th2 or Th17 effector cells 12, or IL-10–secreting cells resembling adaptive Tregs 1, demonstrating that Foxp3-mediated Treg induction, rather ...
“Chimeric antigen receptor (CAR) T cell therapy targeting CD19 has transformed the treatment of refractory B ... including reduction of immunosuppressive regulatory T cells (Tregs), and reprogramming ...
UK start-up Quell Therapeutics has secured a partnership with AstraZeneca focused on cell therapies for autoimmune diseases, with an $85 million upfront payment and which could be worth up to $2 ...
A University professor has found a new way to treat cancer using different cell compounds, like the NR0B2 protein.
Regenerative medicine has the potential to reshape how we treat diseases, offering new hope for patients requiring cell, ...
While the human body’s immune system is generally able to defend against harmful germs, diseases like cancer are trickier to ...
Regenerative medicine holds the extraordinary promise that future patients in need of new cells, tissues or organs will no ...
An emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some cancer immunotherapies, ...