We selected a set of targets to interrogate the immune tumor microenvironment 7: T cells (CD4, CD8), B-cells (B220), myeloid cells including dendritic cells (CD11b, MHC II, CD11c) and functional ...

Prostate cancer vaccines, including dendritic and peptide types, offer hope for improved treatments, but face hurdles in ...

Figure 1: Multiple pro-inflammatory mediators in the tumor microenvironment increase ... tumor growth by preventing the activation of CD4 + and CD8 + T lymphocytes, inhibiting natural-killer ...

The TIME is a dynamic network composed of cancer cells, immune cells, and stromal components. During the early stages of tumorigenesis, the TIME ...

This study reveals distinct immune subpopulations associated with specific myeloma cell genotypes and highlights the central ...

Tumor tissue and ascites from patients with ovarian cancer contain high levels of cells with all the hallmarks of regulatory T cells. These cells migrate into the tumor microenvironment in a ...