Uric acid is a waste product formed when the body breaks down substances called purines. While uric acid should exit through urine, it can sometimes build up in the blood and pass into the kidneys.

Kidney stones are another complication of gout, as is an uncommon form of chronic kidney disease called chronic uric acid nephropathy. Increased blood uric acid levels are associated with a higher ...

The patient was intolerant to allopurinol and had mild renal insufficiency attributed to uric-acid nephrolithiasis and interstitial nephropathy. Investigations Physical examination, laboratory ...

Monosodium urate crystals dissolve and are eliminated from joints and soft tissues as serum uric acid levels drop below its saturating point (400 μmol/l). Time to crystal clearance relates to ...