This article examines viral and non-viral vectors in gene therapy, highlighting their mechanisms, advantages, and limitations in genetic material delivery.

One aspect that signals pandemic potential in a virus is having an RNA, rather than DNA, genome. That’s because the process of copying RNA typically doesn’t include a proofreader like DNA replication ...

Ottawa, Feb. 19, 2025 (GLOBE NEWSWIRE) -- The global viral vector and plasmid DNA manufacturing market size was valued at USD 7.19 billion in 2024 and is expected to be worth around USD 46.02 ...

The path forward for a T-cell-based vaccine against HIV remains unclear, with problems such as vaccine immunogenicity, vector-specific ... and the two copies of viral RNA that are complexed ...

As the particles are often pseudotyped with the envelope of the vesicular stomatitis virus (VSV), the vector can serve to introduce genes ... prevent recombination of replication-competent HIV. All ...

Infection with Zika virus in pregnancy can lead to neurological disorders, fetal abnormalities and fetal death. Until now, ...

This means that the presence of HERV RNA may not be enough to connect the virus to a disease. On the other hand, our research also suggests that HERVs could even be beneficial to people. The most ...

MicroRNAs function by binding to a matching piece of messenger RNA that encodes a protein and decreasing the production of that protein. Viral RNA with a base sequence complementary to that of ...

Several antiviral and anticancer drugs target the incorporation of adenine into DNA or RNA. For example, some nucleoside analog drugs, such as vidarabine and fludarabine, mimic adenine and interfere ...