近日,复旦大学附属肿瘤医院赵森林、李大卫等研究者在 Nature Communications 期刊发表了最新研究成果,揭示 肝转移 灶中的 癌细胞 可借助过表达转录因子WNT11,同时影响CD8 + T细胞的募集、激活和 免疫 ...
The U.S. Food and Drug Administration (FDA) has approved Fapon Biopharma’s Investigational New Drug (IND) application for ...
In summary, this study revealed the role of aging in compromising the anti-tumor immune response of CD8 + T cells and the molecular mechanism involved. Further investigation of inhibitors ...
(b) A closer look reveals eTregs control CD8-EM cells by stopping their division and reducing GzmB while maintaining CD27. (c) Dividing eTregs increase CD98, GLUT1, and CTLA4 proteins, and shows how ...
CD8 + T cells are a crucial component of adaptive immune responses and are particularly important for the control of intracellular pathogens such as viruses as well as anti-tumor responses.
Medicenna Therapeutics (MDNA) announced the presentation of new clinical data from its ongoing ABILITY-1 study evaluating MDNA11 alone or in ...