Conventional chemotherapeutics disrupt mitotic events in proliferating cells. By exploiting the growth fraction differential between tumor cells and those of normal host tissues, tumor reduction ...

Each cell in our body experiences up to tens of thousands of DNA-damaging events per day, primarily from routine cellular ...

Reporting in Cancer Cell, MacDiarmid and colleagues now describe a promising new technology that firmly encapsulates chemotherapeutics into bacterial minicells, which are then guided by antibodies ...