Cyclin-dependent kinases (CDKs) are protein kinases involved in critical cellular processes, such as cell cycle or transcription, whose activity requires association with specific cyclin subunits.

Inside each cell, enzymes called cyclin-dependent kinases (CDKs) bind to cyclins to form complexes that drive mitosis. The CDK2–cyclin A2 complex regulates DNA replication, and the CDK1–cyclin ...

Monte Rosa Therapeutics (GLUE) announced the company will present preclinical data on the potential of its highly selective cyclin-dependent ...

Researchers have developed an innovative approach to treat cancers driven by kinase mutations, specifically targeting B cell ...

The POTAMI-61 study will involve two parts, with Part A enrolling approximately 20 subjects across two cohorts.

When this protein - cyclin-dependent kinase (CDK) - was suppressed, the treatment also prevented a change in the colour of their fur. This leaves the door open for scientists to help delay the ...

Novartis NVS announced that the European Commission (“EC”) has approved its breast cancer drug Kisqali (ribociclib) for a ...

Ensem Therapeutics, Inc. (ENSEM), a pioneering drug discovery and development company that leverages its unique Kinetic ...

That deal included a $50 million upfront payment. CDK inhibitors, which treat cancer by blocking overactive cyclin-dependent kinases, are big business in breast cancer. Earlier this month an ...