(D) Based on the results of cyclin and CDK-knockout studies, scientists have constructed a new threshold model of cell cycle control. Accordingly, either CDK1 or CDK2 bound to cyclin A is ...
Our work showed that CDK5 is activated by cyclin B1 and is required for proper cell division in non-neuronal cells. Indeed, like CDK1, CDK5 is also a canonical cell-division-cycle CDK. We have ...
Researchers have developed an innovative approach to treat cancers driven by kinase mutations, specifically targeting B cell ...
Poster presentation details are below: Author: Molina et al Title: CID-078, a first-in-class oral cyclin A/B-RxL inhibitor ... alterations that cause cell cycle dysregulation.
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