In vector graphics, the two ends of a line (vector). In 2D graphics, each end point is typically two numbers representing coordinates on the x-axis and y-axis. In 3D, each end point is made up of ...

While main results from a platform study of four experimental drugs for amyotrophic lateral sclerosis are negative, it shows ...

A minority of studies used the standard three-point MACE endpoint, and many tweaked their endpoints along the way.

ALS candidates from Biohaven, Prilenia, Clene and UCB have all failed to halt disease progression versus placebo in the ...

The combination therapy failed to beat out the company’s other cancer therapy, Opdivo, in patients living with melanomas.

We used the coefficient of determination R 2 from weighted linear regression models to quantify the association between treatment effects on OS and on the surrogate end points. Authors retain all ...

To try to get a firmer understanding of the phenomenon, the FDA will launch the Digitally-Derived Endpoints for Freezing-of-Gait Detection (DEFoGD) Challenge later this month, looking for ...

Elinzanetant successfully met the primary endpoints of the study demonstrating statistically significant reductions in the frequency of moderate to severe vasomotor symptoms (VMS, also known as ...

CBL-514, the world's first investigational drug for large-area localized fat reduction, has demonstrated significant efficacy in its second and the last Phase 2b study (CBL-0205) before Phase 3. 54.2% ...