Glyburide, metformin HCl; 2.5mg/500mg, 5mg/500mg; tabs. Take with meals. Individualize. Not controlled on diet/exercise (use individual components): initially glyburide 1.25mg and metformin 250mg ...

Data Synthesis: Studies of glyburide and glipizide have found little or no transfer of these drugs across the placenta, whereas metformin and rosiglitazone cross readily. Animal studies have found ...