Gene-editing tools such as CRISPR/Cas9 can be used to create isogenic cell lines, which can be further used to model a specific patient population. An isogenic cell line was created to model ...
(A) Growth curves of wild-type E. coli O157:H7 (squares) and an isogenic mutant of stx2 (circles) in Eagle's minimal essential medium (EMEM) and LB, a medium that is relatively rich in nutrients.