三级淋巴结构(Tertiary lymphoid structures,TLSs)是在慢性炎症、肿瘤等部位的非淋巴组织中发育的异位淋巴器官。目前已经确定了二级淋巴器官发生(secondary lymphoid organogenesis)和三级淋巴结构新生(TLS neogenesis)之间的关键共同特征。TLSs在肿瘤中存在不同的成熟状态,最终形成生发中心(germinal centre ...
Table 2. Distinction between atypical lymphoid proliferations rich in Reed–Sternberg-like cells (reactive immunoblasts) and classic Hodgkin lymphomas. Aspects Atypical lymphoid proliferations ...
We have begun a study of gene expression in lymphoid malignancies by constructing a specialized cDNA microarray, termed the ‘Lymphochip’, that is enriched in genes selectively expressed in ...
Lymphoid proliferations are traditionally thought to be either benign conditions (reactive hyperplasia and lymphadenitis) or malignant lymphomas. However, not all lymphoid lesions at present can ...
Dr El-Sharkawi's group researches chronic lymphocytic leukemia, rare leukaemias and lymphomas as well as early phase trials and drug development. Dima El-Sharkawi was appointed as a Consultant ...
The study, published Oct. 25 in Nature Immunology, provides new information about lymph node-like structures called tertiary lymphoid structures. These structures, which are highly organized ...
Researchers at the Institut Pasteur in France have developed artificial "lymphoid organ-chips" that recreate much of the human immune system's response to booster vaccines. The technology, described ...
The study, published Oct. 25 in Nature Immunology, provides new information about lymph node-like structures called tertiary lymphoid structures. These structures, which are highly organized ...
Dendritic cells are poised to revolutionize oncology. This type of immune therapy shows effectiveness even in late-stage ...
It commonly affects women of African American descent. Shahid Mukhtar and his team — Bharat Mishra, Nilesh Kumar and graduate student YiFei Gou — used single-cell sequencing techniques to pinpoint CD2 ...