Enter Primrose Bio with its offering of commercially available, proprietary, best-in-class RNA polymerases for mRNA synthesis by in vitro transcription (IVT) (Fig. 1). Primrose Bio’s Prima ...

New therapeutic possibilities for various diseases are made possible via mRNA. The adaptability of in vitro transcribed (IVT) mRNA is largely due to its simpler cell-free manufacture, cell cycle ...

Introducing Sanyou Mrna Mab innovative antibody generation technology platform SHANGHAI, /PRNewswire/ -- With the announcement of the 2024 Nobel Prize in Physiology or Medicine, microRNA has once ...

Quality control (QC) is vital to the in vitro transcription (IVT) RNA workflow. Because IVT RNA synthesis generates RNA that scientists use in multiple downstream applications, it is critical to start ...

“Larger mRNA-based therapeutics are synthesised by in vitro transcription, which is not amenable to extensive nucleotide modifications and thus have poor stability when administered into the bod ...

25 affinity solution was designed for the purification and isolation of mRNA of in vitro transcription manufacturing processes. Tailor-made for efficient purification of mRNA constructs, the POROS ...

The major challenge is to define the functions of these mRNA export factors. A further puzzle is that a mammalian homologue of Yra1, ALY, has been shown to bind some transcription factors ...

The new proof of concept study published in ACS Nanoscience Au may be the first to show delivery of both mRNA and siRNA in vivo and in vitro, to enhance and interfere with multiple gene and ...

More information: Byron Brook et al, The BNT162b2 mRNA vaccine demonstrates reduced age-associated TH1 support in vitro and in vivo, iScience (2024). DOI: 10.1016/j.isci.2024.111055 ...