A discovery at Duke-NUS Medical School offers new hope in the battle against pulmonary fibrosis, a debilitating lung ...
在这项研究中,研究人员通过饮食诱导的肥胖和前驱糖尿病小鼠模型,发现巨噬细胞在周围神经病变中起着神经保护作用。巨噬细胞在疾病早期就浸润到完整的周围神经中,其表达谱与神经退行性疾病相关的髓样细胞相似,并且通过 Gal - 3 延缓了终末轴突变性的发生。在 HFHFD 模型中,机械性异常疼痛在疾病早期出现,但 6 个月时会缓解;热痛觉减退在轴突终末变性可检测到之前就已出现,且与 Sarm1 基因相关。
Understanding why newborns, but not adults, can regenerate the heart could lead to treatments that "reprogram" adult ...
An increase in high-fat, high-fructose foods in people's diets has contributed to a dramatic increase in type 2 diabetes.
By analyzing multiple emphysema and COPD patient datasets, SPP1 is significantly upregulated in the lungs of patients, ...
Io Biotech Aps has presented preclinical data regarding their Arg1-derived peptide cancer vaccine IO-112 as a potential immunotherapeutic that would allow controlling the tumor microenvironment.
Finnish researchers show in a new study that pituitary macrophages, the immune cells located in the pituitary gland, help ...
In the infancy of his career, Northwestern University heart researcher Connor Lantz, PhD. made a discovery about infants.
Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.
In a new study published in Cell Reports, Finnish researchers show that pituitary macrophages, the immune cells located in ...
Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...