在这项研究中，研究人员通过饮食诱导的肥胖和前驱糖尿病小鼠模型，发现巨噬细胞在周围神经病变中起着神经保护作用。巨噬细胞在疾病早期就浸润到完整的周围神经中，其表达谱与神经退行性疾病相关的髓样细胞相似，并且通过 Gal - 3 延缓了终末轴突变性的发生。在 HFHFD 模型中，机械性异常疼痛在疾病早期出现，但 6 个月时会缓解；热痛觉减退在轴突终末变性可检测到之前就已出现，且与 Sarm1 基因相关。

Strategies to combat addiction The knowledge of the neurobiology of drugs and the adaptive changes that occur with addiction is guiding new strategies for prevention and treatment, and identifying ...

The MPI for Neurobiology of Behavior – caesar (MPINB) in Bonn focuses on basic research in neuroethology. International researchers at the institute study how the collective activity of vast numbers ...

The Computational Neuroscience Center at Drexel’s Department of Neurobiology and Anatomy brings together a group of computational and experimental researchers with a common interest to understand ...

Caenorhabditis elegans, or C. elegans, is a small roundworm (nematode) usually found in the soil in temperate climates all around the world. It feeds on microorganisms like bacteria and can be most ...

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The first time Kees van Heeringen met Valerie, the 16-year-old girl had just jumped from a bridge. It was the 1980s and van Heeringen was working as a trainee psychiatrist at the physical ...

A planning committee of the National Academies of Sciences, Engineering, and Medicine will host a two-day public workshop that brings together leaders and experts across disciplines and sectors to ...

The UAB Department of Psychiatry and Behavioral Neurobiology is an integral part of one of the nation's largest health systems. Nationally known for our compassionate care, cutting-edge research, and ...

Just like ChatGPT and other generative language models train on human texts to create grammatically correct sentences, a new ...

Akoya Biosciences announced a significant expansion of its product offerings with the introduction of new high-plex neurobiology panels for human and mouse applications, enhancing their recent ...