Anal and perianal complications of Crohn's disease represent a major challenge for both the gastroenterologist and colorectal surgeon. Anoperineal disease is one manifestation of Crohn's disease ...

The Food and Drug Administration (FDA) has granted Fast Track designation to AVB-114 for the treatment of perianal fistulas in patients with Crohn ...

Jennifer Jones, MD, Advanced Fellow in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota William Tremaine, MD, Professor of Medicine ...

"Perianal fistulas are a tremendous challenge for patients and their treating physicians. If the results of the ongoing Phase II trial are consistent with the impact we saw in the Phase I trial ...

Early treatment of pediatric Crohn's disease with anti-tumor necrosis factor medications can substantially reduce the risk of perianal fistulas, a particularly debilitating complication of Crohn's ...

3, 2025 (HealthDay News) -- For pediatric patients with Crohn disease, early anti-tumor necrosis factor-alpha (anti-TNFα) therapy is beneficial in preventing the development of perianal fistula ...