A new study by researchers at the Max Planck Institute for Evolutionary Biology (MPI-EB) sheds fresh light on one of the most ...

Sample, financial and labor requirements are key barriers to scaling up high-content phenotypic discovery efforts. A broadly applicable method overcomes these challenges through experimental ...

研究团队通过单细胞测序技术发现，正常肠道干细胞（intestinal stem cells, ISCs）在癌变过程中会经历"返老还童"式的重编程，进入一种胎儿发育期的特殊状态（oncofetal state, ...

Evolution of a hyper-mutable locus delivers foresight Through the analysis of more than 500 mutations, the study uncovered the emergence of a localized hyper-mutable genetic mechanism in certain ...

Fully definable high content analysis software removes this bottleneck allow for bespoke protocols to be written that will give you phenotypic data on a per object (foci, nuclei, cell), per field and ...

More information: Nuo Liu et al, Scalable, compressed phenotypic screening using pooled perturbations, Nature Biotechnology ...

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