Top-down infliximab plus azathioprine versus azathioprine alone in patients with acute severe ulcerative colitis responsive to intravenous steroids: a parallel, open-label randomised controlled trial, ...

Occasionally in cases of porcine intestinal adenomatosis (PIA) epithelial dysplasia is seen with infiltration of the epithelium into underlying tissues and spread, via the lymphatics, to drainage ...

Knowledge on SARS-CoV-2 infection and its resultant COVID-19 in liver diseases has rapidly increased during the pandemic. Hereby, we review COVID-19 liver manifestations and pathophysiological aspects ...

1 Laboratory for Molecular Liver Cell Biology, Free University Brussels (VUB), Brussels, Belgium 2 Department of Medical Cell Biology and Centre for Liver Research, University of Newcastle-upon-Tyne, ...

The two major forms of inflammatory bowel disease (IBD), encompassing Crohn’s disease (CD) and ulcerative colitis (UC), are chronic immune-mediated conditions characterised by an increased production ...

Objective Tumour heterogeneity represents a major obstacle to accurate diagnosis and treatment in gastric adenocarcinoma (GA). Here, we report a systematic transcriptional atlas to delineate molecular ...

It is widely accepted that glyceryl trinitrate (GTN) effectively dilates the smooth muscles of blood vessels. A similar effect has been postulated on the smooth muscles in the gastrointestinal tract.

1 Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA 2 Department of Surgery, Massachusetts General Hospital and Harvard Medical School, ...

Correspondence to Dr Thomas Berg, Section of Hepatology, Department of Internal Medicine, University Hospital Leipzig, Leipzig 04103, Germany; thomas.berg{at}medizin.uni-leipzig.de Objective ...

Objective Dietary fibres are essential for maintaining microbial diversity and the gut microbiota can modulate host physiology by metabolising the fibres. Here, we investigated whether the soluble ...

Correspondence to Dr. Qingsong Chen, Guangdong Pharmaceutical University, Guangzhou, People's Republic of China; qingsongchen{at}aliyun.com; Dr. Yu Sun, South China Agricultural University, Guangzhou, ...

The Lyon Consensus provides conclusive criteria for and against the diagnosis of gastro-oesophageal reflux disease (GERD), and adjunctive metrics that consolidate or refute GERD diagnosis when primary ...