Budde et al. identified mutations in tRNA-splicing endonuclease subunits in patients with PCH2 or PCH4. Expression studies showed that TSEN54 was highly expressed in the pons, and the cerebellar ...

The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA ... untranslated region (UTR) or leader sequence.