This interaction suggests that ILF3 may facilitate the resolution of telomeric R-loops, thereby preventing abnormal homologous recombination and maintaining telomere homeostasis. The work ...

View Full Profile. Learn about our Editorial Policies. In normal mammalian cells, a small telomeric DNA segment is lost after each cell cycle, gradually eroding to a critical length. At this point, ...

Figure 1: Strategy for detecting inter-telomeric copying of DNA. Figure 2: Detection of plasmid tag DNA at the telomere by FISH. We confirmed the FISH data by Southern-blot analysis of integrated ...