Amit Sharma as the first author, has identified GLUT3, a glucose transporter, as essential to the suppressive function of regulatory T cells (Tregs) in the tumor microenvironment (TME).
or Tregs, for expansion. Triggering checkpoint coinhibitory receptors, which are often upregulated on activated T cells, serves to dampen the level of T-cell activation and functions as a ...
Regulatory T cells (Tregs) have gone from obscurity ... factor Foxp3 in governing Treg differentiation and function. Tregs play essential roles in immune homeostasis and protection against ...