Since these ES cells contain the exon 11 deletion found in mice that conditionally develop mammary gland tumors, the homologous repair defect is, thus far, found to correlate with tumorigenesis.

However, mechanistic studies to support the conclusion that mitochondrial function is increased in the tumours remain incomplete and would benefit from experiments that would directly interrogate ...

A recent study published in the Journal of Clinical Investigation by researchers at Johns Hopkins University School of Medicine and collaborators identified HMGA1 as a key epigenetic regulator that ...

The team's findings are published in the journal Advanced Science. The research team discovered that normal cells can enter ...

Scientists have found a molecular switch that reverses cancer cells in the body back to their normal, healthy state.

More information: Qian Zhang et al, Deciphering gastric inflammation-induced tumorigenesis through multi-omics data and AI ...

CIRBP Family, Tumors, Molecular Mechanisms, RNA-Binding Proteins, Cellular Stress Share and Cite: Cai, Y. , Wang, T. and Zhan ...

Intercellular communication between tumor cells and cancer-associated fibroblasts (CAFs) plays a key role in tumorigenesis ...

Scientists have discovered a molecular switch that can reverse cancer—turning cancer cells back into their healthy counterparts. The revelation by researchers from the Korea Advanced Institute of ...

Genetic mutations in FGFR2 drive tumorigenesis, particularly in endometrial cancer, but Ding’s evidence shows that epigenetic modifications similarly promote oncogenesis. “We’re very excited about ...